Mixed Lymphocyte Culture in Histocompatibility Testing for Familial Renal Transplantation
نویسندگان
چکیده
منابع مشابه
Successful bone marrow transplantation against mixed lymphocyte culture barrier.
If bone marrow transplantation is to become widely applicable in the treatment of patients with leukemia and aplastic anemia, the necessity to have a perfectly histocompatible donor must be overcome. In an effort to define the roles of HL-A type and mixed lymphocyte culture (MLC) reactivity in the determination of successful engraftment and the occurrence of graftversus-host disease (GVHD), we ...
متن کاملAddition of exogenous cytokines in mixed lymphocyte culture for selecting related donors for bone marrow transplantation.
CONTEXT Mixed lymphocyte culturing has led to conflicting opinions regarding the selection of donors for bone marrow transplantation. The association between a positive mixed lymphocyte culture and the development of graft-versus-host disease (GVHD) is unclear. The use of exogenous cytokines in mixed lymphocyte cultures could be an alternative for increasing the sensitivity of culture tests. ...
متن کاملRelationship of Mixed Lymphocyte Culture Response to Hl-a Histocompatibility Antigens
The influence of varying degrees of incompatibility for HL-A antigens on one-way mixed lymphocyte cultures (MLC) has been investigated. Reactions have been compared to a simple expression of HL-A antigens, allele compatibility, and a proposal considering the potential influence of antigen matching in relationship to allele compatibility. As expected, HL-A compatibility was associated with nonst...
متن کاملSHORT COMMUNICATION Mixed Lymphocyte Culture Reactivity and H-2 Histocompatibility Loci Diff erencesl”
The relationship between the major histocompatibility systems as defined serologically and by the mixed leukocyte culture (MLC) test is one which has received attention in both man (1) and mouse (2). In man, studies within families suggest that cells of siblings who inherit the same HL-A chromosomes from their parents and thus are serologically identical at HL-A do not stimulate in the MLC test...
متن کاملLymphocyte reactivity in rheumatoid arthritis. Mixed lymphocyte culture.
Lymphocyte function in rheumatoid arthritis has been assessed by the mixed lymphocyte culture assay. In contrast to previous studies, no difference was found between lymphocytes from healthy volunteers and patients with rheumatoid arthritis. An occasional patient's lymphocytes failed to respond on a given day, but were normal on restudy. All 44 arthritic patient's lymphocytes underwent blast tr...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1972
ISSN: 0003-4932
DOI: 10.1097/00000658-197206010-00012